PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMC) BANKING

While the most commonly known cells in the blood are the Red Blood Cells (RBCs) or Erythrocytes, nothing less of importance are the White Blood Cells (WBCs) which consist of cells with multi-lobulated nucleous and granules (termed Polymorphonuclear) which are the Neutrophils, Eosinophils, and Basophils), and  cells with a single nucleous (Mononuclear) which are the Lymphocytes and Monocytes).

 

Also known as Peripheral Blood Mononuclear Cells (PBMCs), they circulate in the blood stream through the body and play an important role in the human immune system. They are used by researchers and clinicians in areas such as immunology, cancer treatment, regenerative and personalized medicine.

Among the cells in PBMC, T-lymphocytes or T-cells contribute greatly in our defence against diseases such as infections and cancer. Recent advances in science discovered a way to modify these T-cells to more efficiently recognize and kill cancer cells. Known as CAR-T cell treatment, such technology has helped cancer sufferers in reducing the tumour burden and even achieve remission.

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Click here to learn more about CAR-T cell technology and CytoMed’s patented CAR-T technology.

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PBMCs can also be used to generate induced Pluripotent Stem Cells (iPSCs) which can serve as an unlimited source of your own cells and is a highly potential stem cells that can be transformed into many types of functional cells for future regenerative medicine and disease treatments.

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Click here to learn more about CytoMed's patented technology in generating iPSCs from PBMCs.

 

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Click for more Frequently Asked Questions (FAQ) on IPSCBank's PBMC Banking.

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